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Preheat oven to 400 degrees F.
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Spray a 12-cup muffin pan with cooking spray and set aside. You can also use baking cup liners.
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In a large mixing bowl, whisk together egg, oil, pumpkin spice, and vanilla. Whisk in the pumpkin and sugar, until smooth.
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In a separate bowl stir together flour, baking powder, and salt. Add to wet ingredients and stir just until dry ingredients are incorporated.
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Divide muffin mixture evenly between 12 muffin cups in the muffin pan.
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Using a handheld electric mixer, blend cream cheese, brown sugar blend, and vanilla until smooth, on the lowest setting.
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Using a spoon, drop a dollop of the cream cheese mixture into the center of each muffin. Use a butter knife or toothpick to swirl the cream cheese through each muffin.
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Bake in preheated oven for 15-20 minutes, or until toothpick inserted comes out mostly clean.
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Transfer from muffin pan to wire rack to cool.
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The muffin will be dense.